Guard Column Starter Set, Bidentate C8, complete with 5 each 2.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40008‑PG1 Cogent Bidentate C8 Guard Column Starter Set provides a complete, ready‑to‑use solution for protecting analytical HPLC columns from contamination, particulates, and strongly retained compounds.
This starter kit includes:
(5) Bidentate C8 guard cartridges
2.0 mm ID × 10 mm length
Packed with 4 µm, 100 Å TYPE‑C™ silica hydride phase
The guard holder is compatible with all Cogent TYPE‑C™ guard cartridges, allowing for easy cartridge replacement without changing your system configuration.
Each cartridge is individually packaged in closeable Delrin™ cases, preventing contamination, drying, or damage prior to use.
Designed for 2.1 mm Analytical Columns
This kit is specifically optimized for:
2.1 mm ID analytical HPLC columns
LC‑MS workflows and low‑flow systems
Methods requiring high sensitivity and reproducibility
Using a properly matched guard column ensures:
Minimal impact on peak shape and efficiency
Consistent performance across runs
Extended analytical column lifetime
Why Use a Guard Column Starter Kit
Analytical columns are highly susceptible to:
Particulate contamination
Strongly retained compounds
Sample matrix buildup
Irreversible fouling
The 40008‑PG1 starter kit helps prevent these issues by acting as a sacrificial protection layer, ensuring:
Extended column lifetime
Reduced risk of column fouling
Improved reproducibility
Lower cost per analysis
In typical laboratory use, the included five cartridges often provide protection for the full lifetime of an analytical column, depending on sample cleanliness and workflow conditions.
Bidentate C8 Guard Phase Advantages
Using the same stationary phase as your analytical column ensures:
Matched selectivity and retention behavior
No unexpected chromatographic changes
Smooth transfer of analytes to the analytical column
Compared to C18 phases, Bidentate C8:
Reduces excessive hydrophobic retention
Improves recovery of amine-containing compounds
Provides alternative selectivity for complex samples
Supports faster equilibration and throughput
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Reduced silanol activity
Improved peak shape for basic compounds
Lower secondary interactions
Faster Equilibration
Shorter method cycle times
Improved lab productivity
Durability
Resistant to hydrolysis
Long column and cartridge lifetime
Stable under demanding analytical conditions
Typical Applications
LC‑MS and HPLC analytical methods
Pharmaceutical and metabolite analysis
Samples with complex matrices or contaminants
Amine‑containing compounds
Routine analytical workflows requiring consistency